» Phosphodiesterase : 2012 Answer if you can..

Phosphodiesterase

What is Phosphodiesterase?
Phosphodiesterase is any protein that breaks a phosphodiester bond. Normally, people talk of phosphodiesterase is concern to cyclic nucleotide Phosphodiesterases, which have great clinical significance and are, depict below. Phosphodiesterase were separate from rat brain expend polyacrylamide gel electrophoresis in the early 1970s. And were soon afterward shown to be selectively suppressed by a variety of drugs in brain and other tissues.

Classification and Nomenclature
Amino acid sequences
Substrate specificities
Regulatory properties
Pharmacological properties
Tissue distribution.

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